Osmosis Jones

"Every body needs a hero."

A white blood cell policeman, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.

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Chris Rock

Osmosis Jones (voice)

Laurence Fishburne

Thrax (voice)

David Hyde Pierce

Drix (voice)

Brandy Norwood

Leah (voice)

Elena Franklin

Shane Detorre

Bill Murray

Frank Detorre

William Shatner

Mayor Phlegmming (voice)

Ron Howard

Tom Colonic (voice)

Kid Rock

Kidney Rock (voice)

Molly Shannon

Mrs. Boyd

Chris Elliott

Bob

Jonathan Adams

Officer Tom (voice)

Carlos Alazraqui

Spanish Germ (voice)

Keith Anthony

Additional Character Voices (voice)

Eddie Barth

Conductor (voice)

Sally Brooks

Additional Character Voices (voice)

Rodger Bumpass

Joe Cramp / Announcer for Nerve News Network (voice)

Michael Carven

Additional Character Voices (voice)

Paul Christie

Dan Matter / Germ (voice)

Janis Dardaris

Additional Character Voices (voice)

Wendy Dillon

Additional Character Voices (voice)

Antonio Fargas

Chill the Flu Shot (voice)

Eddie Frierson

Frank Police Department Officer (voice)

Donald Fullilove

Doughnut (voice)

Jackie Gonneau

Additional Character Voices (voice)

Shannon Gregory

Additional Character Voices (voice)

Richard Steven Horvitz

Additional Character Voices (voice)

Rif Hutton

Charlie (voice)

Art Kimbro

Additional Character Voices (voice)

Joyce Kurtz

Additional Character Voices (voice)

Anne Lockhart

Female Red Blood Cell (voice)

Sherry Lynn

Trudy (voice)

Danny Mann

Musician Cell (voice)

Mickie McGowan

Brain Librarian (voice)

Kenny Olson

Kidney Rock Band (voice)

Jason Krause

Kidney Rock Band (voice)

Joe C.

Kidney Rock Band (voice)

Stefanie Eulinberg

Kidney Rock Band (voice)

Jimmie Bones

Kidney Rock Band (voice)

Uncle Kracker

Kidney Rock Band (voice)

Joel Silver

Police Chief (voice) (uncredited)

David Ossman

Scabies (voice) (uncredited)

John Melendez

Artie (voice)

Héctor Mercado

Additional Character Voices (voice)

Paul Pape

Male Red Blood Cell #2 (voice)

Marilyn Pasekoff

Additional Character Voices (voice)

Chris Phillips

Firefighter Doug (voice)

Lynne Redding

Additional Character Voices (voice)

Al Rodrigo

Frank Police Department Walkie Talkie (voice)

Herschel Sparber

Bruiser (voice)

Doug Stone

Police Officer Jamie (voice)

Steve Susskind

Mob Boss Germ (voice)

Keri Tombazian

Additional Character Voices (voice)

Paul Tuerpe

Additional Character Voices (voice)

Robert Wisdom

Big Germ (voice)

Danny Murphy

Zookeeper Superintendent

Jack McCullough

Zookeeper

Will Dunn

Oyster Boy

Jackie Flynn

School Janitor

Kelsey Jordan

Bus Girl #1

Abe Farrelly

Bus Girl #2

Jesse Peter

Laughing Boy

John-Eliot Jordan

Pea Soup Manager

Nancy Byers

Pea Soup Supervisor

Kevin J. Flynn

Docky's Clamshack Waiter

Sean Gildea

Dreamy Photographer

Kathryn Frick

Nurse #1

Nikki Tyler-Flynn

Nurse #2

Elizabeth Jordan

Nurse #3

Zen Gesner

ER Doctor #1

Marc Hyman

ER Doctor #2

Zak Penn

ER Doctor #3

Diane Conrad

Zoo Visitor or Staff

Judith Conrad

Zoo Visitor or Staff

Thomas Jordan

The Zoo Visitor or Staff

Sydney J. Bartholomew Jr.

Zoo Visitor or Staff

Erica Johnson

Zoo Visitor or Staff

Bo Cleary

Pea Soup Staff

Bruce McIntyre

Pea Soup Staff

Colleen O'Donnell

Docky's Clamshack

Docky

The Bikini Gang

Joe Murphy

The Bikini Gang

Brian Mone

Police Officer

Sean Fitzgerald

Police Officer

Grace Costa

ER Nurse

Emily O’Donnell

School Girl

Crew

Bobby Farrelly

Director

Bobby Farrelly

Producer

Peter Farrelly

Producer

Zak Penn

Producer

Bradley Thomas

Producer

Randy Edelman

Original Music Composer

Mark Irwin

Director of Photography

Lois Freeman-Fox

Editor

Stephen Schaffer

Editor

Sam Seig

Editor

Peter Farrelly

Director

Adam Beck

Animation

Paul Dutton

Animation

Jeannine Berger

Post Production Supervisor

Audrey Stedman

Layout

Karen Hamrock

Layout

Bob Camp

Storyboard

Eddie Rosas

Animation

Bill Perkins

Layout

Jennifer Yuan

Layout

Earl A. Hibbert

Visual Effects

Marc S. Fischer

Co-Producer

Aaron Parry

Associate Producer

John Walker

Associate Producer

Arlan Jay Vetter

Art Direction

Chris Aguirre

Visual Development

Barry Caldwell

Storyboard

Ruben Chavez

Visual Development

Katherine C. Concepcion

Art Department Manager

Ricardo F. Delgado

Visual Development

Hani D. El-Masri

Visual Development

Jeff Etter

Visual Development

Steve Fonti

Storyboard

Darek Gogol

Visual Development

Daan Jippes

Storyboard

Kevin Johnson

Visual Development

Leon Delaney

Stunt Coordinator

John Bermudes

Special Effects

John Harajovic

Special Effects

William 'Billy Jack' Jakielaszek

Special Effects Coordinator

Carol Koch

Sculptor

Craig R. Maras

Animation

Randy Sanchez

Animation

James P. Alles

Layout

John Williamson

Animation

Joe Giampapa

Animation

Sam Chou

Animation

Shane Prigmore

Animation

Fred Cline

Visual Development

Stephan Franck

Lead Animator

Ian Mah

Visual Effects Supervisor

Darlie Brewster

Supervising Animator

Rick Montgomery

Casting

Steven Burch

Special Effects Supervisor

Sydney J. Bartholomew Jr.

Production Design

Scott Jacobson

Set Decoration

Pamela Withers

Costume Design

Brenda McNally

Hair Department Head

Joe Rossi

Makeup Department Head

Hal Olofsson

First Assistant Director

Ken Ross

Music Supervisor

Randy Thom

Sound Designer

Dennis Edwards

Producer

Alan J. Hagge

Systems Administrators & Support

Louis Gonzales

Layout

Ricardo Curtis

Supervising Animator

Dean Wellins

Supervising Animator

Marc Hyman

Writer

Steve Pilcher

Production Design

Michel Gagné

Visual Effects Designer

Piet Kroon

Animation Director

Tom Sito

Animation Director

Richard Bazley

Supervising Animator

Tony Fucile

Supervising Animator

Wendy Perdue

Supervising Animator

Mark Kausler

Storyboard

Duncan Marjoribanks

Lead Animator

Lennie K. Graves

Lead Animator

Mike Nguyen

Lead Animator

Fergal Reilly

Storyboard

Jeff Siergey

Storyboard

Hank Mayo

Storyboard

Moroni Taylor

Storyboard

Stephan Franck

Storyboard

Wilbert Plijnaar

Storyboard

Peter Sohn

Animation

T.J. House

Animation

Mark Kausler

Animation

Barry O'Donoghue

Animation

Craig Valde

Animation

Mark Andrews

Head of Story

Jae H. Kim

Animation

Gabe Hordos

Animation

Troy Quane

Animation

Daniel Lafrance

Animation

Richard Baneham

Animation

Frank Molieri

Animation

Mike Chavez

Animation

Jim Van der Keyl

Animation

Ruth Daly

Animation

Melina Sydney Padua

Animation

Michael Venturini

Animation

Ralph Fernan

Animation

Chris Waugh

Animation

Andrew L. Schmidt

Animation

David A. Zaboski

Animation

Holger Leihe

Animation

Line Korsgaard Andersen

Animation

Morgan Ginsberg

Animation

Keith Nicholson

Animation

Daryl Graham

Animation

Dennis Pena

Animation

Shannon Penner

Animation

Trevor Deane-Freeman

Animation

Satjit Matharu

Animation

Tony Tupilano

Animation

Kevin Micallef

Animation

Stephen Baker

Animation