The hilarity begins when professor Sherman Klump finds romance with fellow DNA specialist, Denise Gaines, and discovers a brilliant formula that reverses aging. But Sherman's thin and obnoxious alter ego, Buddy Love, wants out...and a big piece of the action. And when Buddy gets loose, things get seriously nutty.
Sherman Klump / Buddy Love / Granny Klump / Mama Klump / Papa Klump / Young Papa Klump / Ernie Klump / Lance Perkins
Denise
Dean Richmond
Jason
Denise's Father
Denise's Mother
Leanne Guilford
Ernie Klump, Jr.
Issac
Restaurant Manager
Restaurant Trainee
Dr. Knoll
Bright Student
Claudine
Old Willie
Chantal
Stripper
Preacher
Bridesmaid
Bridesmaid
Party Guest / Bridesmaid
Party Guest
Mrs. Dudikoff
Receptionist
Man in Bathroom
Man in Bathroom
Zeke
Baby Buddy
Baby Buddy
Baby Buddy
Boardroom Member
Boardroom Member
Guy in Elevator
Dancer
Dancer
Dancer
Dancer
Buddy at 15
Sweet Old Lady with Dog
Buxom Student
Fraternity Student
Lecture Student
Heavyset Woman
Krusty Reporter
Cab Driver
Four Star General
Scientist
Scientist
Newscaster
Scared Popcorn Man
Scared Popcorn Man
Scared Hot Dog Vendor
Scared Little Girl
Denise's Nosy Neighbor (uncredited)
Director
Director of Photography
Editor
Producer
Executive Producer
Executive Producer
Executive Producer
Executive Producer
Executive Producer
Screenplay
Screenplay
Screenplay
Screenplay
Music Coordinator
Makeup Designer
Original Music Composer
Characters
Story
Story
Story
Music Supervisor
Music Supervisor
Costume Design
Special Effects Makeup Artist
Visual Effects Supervisor
Associate Producer
Co-Producer
Co-Producer
Production Design
Stunt Coordinator
Stunt Coordinator
Art Direction
Set Decoration
Camera Operator
Still Photographer
Script Supervisor
Unit Publicist
Sound Mixer
Boom Operator
Cableman
Makeup Department Head
Writer
Title Designer