
Season 4 of A.P. Bio continues the show's evolution into a high-energy, absurdist ensemble comedy. Released on Peacock, it focuses on Jack Griffin finally embracing his role as a chaotic mentor to his students while navigating his own unresolved family trauma.

A tornado puts the school on lockdown. The kids write fan fiction about faculty members.

Jack has the students form a fake cult to sabotage Principal Durbin's new school uniforms.

Jack attempts to get closer with the guys at work. Helen helps Principal Durbin grow a backbone.

Jack tries to expose his allegedly reformed deadbeat dad. A witch shakes up the Whitlock High staff.

Jack finds out he's his girlfriend's therapy homework. Principal Durbin goes undercover.

Victor sends Ashlanda a risqué photo. Grace and Anthony try to set up Mary and Principal Durbin.

A jealous Jack crashes his girlfriend's dinner with a male friend. Helen rebounds after a breakup.

Jack's students steal his Harvard pen. Principal Durbin fails the superintendent's inspection.