In the first of a new series Jonathan meets Liverpudlian funny man John Bishop, the sexiest scientist on the planet Professor Brian Cox, and one of the biggest new acts of 2012 - Lana Del Rey.
In this week's show, Jonathan welcomes Oscar winner Emma Thompson, Take Me Out presenter Paddy McGuinness and Hollywood star Brooke Shields. There is also music from Florence and the Machine.
Jonathan's guests this week include Daniel Radcliffe, Sir David Attenborough and Mighty Boosh star Noel Fielding. Plus there is music from Seal.
This week, Jonathan welcomes Downtwon Abbey star Hugh Bonneville, muppet legends Kermit and Miss Piggy, and comedian Jack Whitehall. Plus Arctic Monkeys perform live in the studio.
This week, Jonathan is joined by superstar footballer David Beckham, Scottish comedian Kevin Bridges and Jessie J, who also sings live.
Jonathan welcomes two-time Oscar winner Denzel Washington, Keira Knightley and actor Tom Hardy. Plus the legendary Dionne Warwick sings live in the studio.
Jonathan welcomes John Hurt, Christina Ricci and Celebrity Juice's Keith Lemon, Fearne Cotton and Holly Willoughby. There is also music from LMFAO.
Jonathan welcomes another star-studded and eclectic line-up to the show as he chats to Sean Bean, boy band JLS and boxer Amir Khan. With music from Brighton hip hop duo Rizzle Kicks.
Jonathan's guests this week include soul legend Lionel Richie, Michael Ball and Imelda Staunton from stage musical Sweeney Todd, and Rihanna, who also performs.
Jonathan welcomes Kiefer Sutherland, Mamma Mia! actress Amanda Seyfried and ex-England cricket star Freddie Flintoff. There is also music from rock legend Paul Weller.
Joining Jonathan today are boxing legend Sugar Ray Leonard, comedian Sarah Millican and fashion guru Gok Wan. Live music comes from Snow Patrol.
Jonathan welcomes Hollywood star Danny DeVito, comedian Dara O'Briain and Britain's Got Talent judges Simon Cowell and David Walliams. There is also a performance from Labrinth. Last in Series 2.