The story of a shady corporation called "Vault-Tec" who constructed underground vaults to protect American citizens from a potential nuclear war.
The creation of, and tales surrounding a race known as "Super Mutants".
A look at the faction called "The Brotherhood of Steel" known for hoarding pre-war technology, specifically their time spent on the west coast of the US.
The story of "The Brotherhood of Steel" on the less civilized east-coast United States.
A look at an institution known as "The Enclave" both before and after the war.
The history of the "New California Republic" (or NCR) and their attempts to bring democracy and law into the post-apocalypse.
The history and ideologies of the NCR's biggest adversary, "Caesar's Legion".
How the New Vegas strip became prosperous in the post-apocalypse and the mysterious man behind it all named Mr. House.
The story of a raider tribe called the "Great Khans" known for drug trafficking.
The history and creation of creatures called "Ghouls" who began to appear in the post-apocalypse in various forms.
The story of a man named "Ulysses", a former member of Caesar's Legion who wears a flag of the old world on his back sending coded messages to an unknown person.
A closer look at the members of Caesar's Legion, specifically their Legates.
Various stories of different religions from before and after the war.
The story of a crater known as the "Big MT" where morally reprehensible scientific experiments take place.
The theories surrounding the possible existence of aliens, taking into account both arguments for and against the claims.
The origins of the post-war caravan company know as the "Crimson Caravan Company" and their position today.
The stories surrounding the mysterious and extremely dangerous "Sierra Madre Casino".
The story of ghoul named Harold is told; the Storyteller gets inspired.