01. Death By Design
Mark's office decorator is murdered.
02. Blind Man's Bluff
Young woman is in a car accident and goes blind, Mark must figure out who committed the murder.
03. Sleight-of-Hand
A body found on the beach turns out to be Jim, the hospital janitor, but when his twin brother Jeff shows up to identify the body, Mark and Steve become suspicious.
04. By Reason of Insanity
Dr. Mark Sloan tries to save one of his former students, a schizophrenic, from a murder charge, but is challenged by the man's seemingly incoherent babbling.
05. The Patient Detective
Steve nearly dies in a car accident and think a murder happens. No one believes him.
06. The Cradle Will Rock
A nurse's husband is murdered and a teen who works at the hospital and who also had a torrid love affair with the nurse is the prime suspect, but Mark isn't convinced that the young man is the killer.
07. Hot House
An abusive man who, along with four other people, was a contestant on a reality show is murdered while living in a house that is monitored 24 hours a day. After the killing, Mark enters the house as the man's replacement to see if he can uncover what happened.
08. All Dressed Up and Nowhere to Die
Mark goes after a man who killed a groom on his wedding day.
09. Confession
Dr. Mark Sloan, Lt. Steve Sloan and Dr. Amanda Bentley become involved when a priest is accused of murdering an old friend.
10. Playing God
Dr. Mark Sloan seeks the murderer who killed a med student, drained his blood, and stored him in the Community General morgue.
11. Less Than Zero
An actress with an eating disorder dies from an apparent heart attack. Mark believes her nutritionist murdered her.
12. Sins Of The Father (1)
A young woman is assassinated while Dr. Mark Sloan is examining her, setting off an investigation that plunges Mark into dark memories of his own childhood.
13. Sins Of The Father (2)
Mark must find out why his dad left him as a child.
14. You Bet Your Life
Dr. Mark Sloan investigates the apparent suicide of a gifted heart surgeon who was also a compulsive gambler.
15. Bachelor Fathers
Dr. Mark Sloan tries to solve the murder of a young woman whose twin sister claims that Dr. Jesse Travis fathered her infant son.
16. Being of Sound Mind
Dr. Sloan tries to save Jesse and Amanda from a murderer who is out to kill them in order to obtain a multi-million dollar inheritance.
17. Dance Of Danger
A Tabloid-news paper reporter gets caught up in a murder investigation when one of her sources is stabbed to death on a dance floor.
18. The Red's Shoes
Dr. Sloan tries to Amanda when she becomes involved in an incident involving the Chinese government.
19. No Good Deed
Dr. Sloan investigates a controversial attorney who confesses to murder while near death but recants after he recovers.
20. Deja Vous - Deadly Mirage (1)
While deeply disturbed that his son, Lt. Steve Sloan, is falling in love with a woman who is a dead ringer for his murdered former girlfriend, Dr. Mark Sloan begins watching his neighbors through binoculars and becomes convinced that one of them is a murderer.
21. On the Beach - Deadly Mirage (2)
While deeply disturbed that his son, Lt. Steve Sloan, is falling in love with a woman who is a dead ringer for his murdered former girlfriend, Dr. Mark Sloan begins watching his neighbors through binoculars and becomes convinced that one of them is a murderer.
22. The Blair Nurse Project
When a filmmaker begins using Community General Hospital as the location for an eerie documentary, Dr. Sloan discovers it may be haunted.