After being wounded by assassins in the field, Sandra West enlists the aid of the eccentric, Doctor Mufungo, surgeon to the spies.
On a family vacation to Costa Rica, Sandra's mother sneaks off on a secret mission of her own.
Sandra West acts as an observer while Bibi goes on her first mission: To deliver a bag of spy masks to the Susquehanna Spy ask Company.
An old family friend (an ex European crime boss), enlists Sandra to take down a new crime lord, trying to muscle in on his business.
Sandra recounts her vast martial arts training and how it has come in handy during her years in the field.
Sandra responds to an urgent message from Jimmy Burbank concerning arms dealers, while The Fez is kidnapped by an unknown spy organization.
Sandra tracks a mysterious creature that is assassinating T.H.E.M. agents.
Sandra West infiltrates Zombie Island, a THEY base and penal colony, to rescue The Fez.
As Sandra and The Fez try to escape from Zombie Island, they are hunted by a deadly T.H.E.Y. tracker known as "The Hyena".
The Hyena seeks revenge on Sandra West for wounding her and successfully rescuing The Fez from Zombie Island.
The Hyena encounters a rival agent, en route to bringing Sandra West to Sue Muru for a five million dollar reward...and the battle is on.
An old nemesis and chess champion, decides to challenge Sandra to a game of chess, with very high stakes.