During World War II, a junior American Army officer, Lt. Peter Stirling, gets sent to the psychiatric ward whenever he insists that an Army mule named Francis speaks to him.

In this funny sequel to the popular Francis the Talking Mule, the talkative Mule and his pal Peter get a job working on a horse-breeder's ranch. They end up saving it from financial ruin when Francis, who has the inside track with the racehorses, provides Peter with names of the winners before the races are run. Sure enough Peter finds himself with a fistful of cash and uses it to buy a racehorse for the farm. Unfortunately, the horse he chooses is suffering from a debilitating lack of confidence. When not dealing with the mare, Peter finds time to court the horse breeder's niece and trying to avoid the gangsters who want in on the winnings.

Francis the talking mule gets his owner in and out of trouble while he is taking basic training at West Point.

A man who has a talking mule gets a job on a newspaper, and both get mixed up in a murder trial.

Peter Stirling (with his old friend the talking mule) is recalled to active duty...in the WACs!

In the U. S. Army intelligence office, bumbling lieutenant Peter Stirling receives a coded message from his friend, Francis, a talking mule. The note urges Pete to hurry to the Coronado, California naval base, where Francis is about to be sold as surplus. Pete rushes to the train station, but before he can board, nurse Betsy Donevan mistakes him for her shell-shocked brother, Navy boatswain Slicker Donevan. She tries to forcibly remove his uniform so he will not get into trouble for impersonating an Army officer. Finally she realizes that Pete is not Slicker but merely his mirror image.

A Ha-Ha-Haunted House Has Got 'Em! ...and it's every ghost for himself!