Sakuragi and the Shohoko team takes on Oda and Takezono High School. This is Sakuragi's second match as he faces Oda, a basketball player who went to the same junior high.

Set during the Inter High Championships, Shohoku take on Tsukubu, one of this year's dark horses. It's a clash of acquaintances as Anzai will face his former student which is now the coach of Tsukubu, while Akagi & Kogure meet Godai their former classmate and Tsukubu's captain. Finally Sakuragi is irked by the presence of Nango, Tsukubu's center, who vies for Haruko's attention.

After losing the titanic match against Kainan High, Team Shohoku and a newly shaven Hanamichi Sakuragi are challenged to an exhibition match by virtual basketball unknowns Ryoukufu High. Coach Anzai sees this as an opportunity for Shohoku to regain their confidence, but Ryoukufu are revealed to have a newly assembled championship calibre lineup and may give Sakuragi & Co their toughest test yet.

Ichiro Mizusawa, a player from Rukawa's old junior high school, Tomigoaka, is diagnosed with a crippling leg condition and wants to play one last game with Rukawa. Hanamichi sets out to help the boy and fulfill his wish.

Shohoku's “speedster” and point guard, Ryota Miyagi, always plays with brains and lightning speed, running circles around his opponents while feigning composure. In his second year of high school, Ryota plays with the Shohoku High School basketball team along with Sakuragi, Rukawa, Akagi, and Mitsui as they take the stage at the Inter-High School National Championship. And now, they are on the brink of challenging the reigning champions, Sannoh Kogyo High School.