Brothers John and Matt have inherited an island cabin from their recently deceased uncle. Along with Matt's girlfriend, Nicki, and other mutual friends, the siblings travel to the cabin for a relaxing weekend getaway. But, not long after arriving, the group is besieged by ravenous dogs. They watch in horror as another vacationer, Luke, is eaten alive. Soon, they discover a training facility where the dogs have been bred to kill.

When Violet accepts an invitation to a private island with some of the world's most famous social influencers, she expects a weekend of unrivaled viral opportunity. She soon becomes part of her own horrific reality show when the guests are pitted against each other to capture the island's legendary man-eating dogs before they become victims of the monstrous canines.