At the height of the Vietnam War, former US special operations commander codenamed Drake went rogue and captured a powerful Christian relic. His intent was to sell the relic on the black market getting revenge on his former country and the brother that he believed betrayed him. The last hope of retrieving the relic and preventing the destruction of the free world rests in the hands of special operations team leader Captain William H. Frost who is haunted by events that occurred during previous past military conflicts. Captain Frost's final mission is to retrieve the relic and find redemption for past sins.

Years after the end of the Blood and Water, Captain Frost (now a zombie) emerges from the shadows and begins his quest to rule the world. With the help of Drake, his undead army, and the Spear of Destiny, the only thing that stands in his way is a group of college students. Jake, the son of Jacobs, Bekah, Terry, and Bird. Jake's world is turned upside down when he's attacked by a zombie. He must learn to accept his destiny and embrace his past if he wants to save the world from Frost's wrath. But, he needs to watch his back. Some of his allies might not be as loyal as he thinks...

With a vampire cult leader wielding sinister powers over her hometown, a religious studies student discovers her ancestral destiny in terminating the evil forces preying upon the once bucolic town of Hillville.